Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.
The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.
Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
Read More
9
Vitamin E hydrogel aids heart repair
Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair.
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.
In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.
While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
Read More
9
Vitamin E reduces heart risks
Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia.
We investigated how vitamin E treatment could impact heart health during severe hypoglycemia in insulin-deficient diabetic rats. In our study, we randomly divided the rats into two groups—those receiving vitamin E and control rats.
Remarkably, we found that treated rats experienced threefold less cardiac oxidative stress, sixfold lower mortality, and sevenfold fewer heart block incidents compared to the controls.
These findings suggest that vitamin E might help reduce fatal heart risks linked to severe hypoglycemia in diabetes, highlighting its potential role in protecting heart health for those suffering from type 1 diabetes.
Read More
Most Useful Reviews
9
Heart disease protection
22 people found this helpful
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
Read More
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
Read More
9
Heart disease control
5 people found this helpful
Once derided, vitamin E now receives significant attention for its role in preventing heart disease. Its natural forms are more effective, and it shows promise for joint inflammation when taken with vitamin A.
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.
In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.
While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
Read More
9
Vitamin E reduces heart risks
Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia.
We investigated how vitamin E treatment could impact heart health during severe hypoglycemia in insulin-deficient diabetic rats. In our study, we randomly divided the rats into two groups—those receiving vitamin E and control rats.
Remarkably, we found that treated rats experienced threefold less cardiac oxidative stress, sixfold lower mortality, and sevenfold fewer heart block incidents compared to the controls.
These findings suggest that vitamin E might help reduce fatal heart risks linked to severe hypoglycemia in diabetes, highlighting its potential role in protecting heart health for those suffering from type 1 diabetes.
Read More
8
Vitamin E linked to heart health
Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.
The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.
Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
Read More
8
Antioxidants may benefit heart health
Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study.
We set out to understand how dietary antioxidants influence the thickness of carotid arteries in patients with coronary heart disease (CHD). In a five-year study involving 805 participants, we compared the effects of a Mediterranean diet and a low-fat diet on carotid intima-media thickness (IMT-CC).
Our findings revealed that higher total antioxidant intake was linked to a decrease in IMT-CC, particularly with the Mediterranean diet. This suggests that consuming more antioxidants might help in reducing atherosclerosis progression in these patients.
Read More
8
Vitamin E shows cardioprotective promise
A prospective study to evaluate the efficacy and safety of vitamin E and levocarnitine prophylaxis against doxorubicin-induced cardiotoxicity in adult breast cancer patients.
We explored the protective effects of vitamin E and levocarnitine on heart health in women undergoing treatment with doxorubicin for breast cancer. In a well-structured study involving 74 patients, those receiving the vitamin combination experienced significantly lower cardiac enzyme levels and fewer heart-related issues compared to those who did not.
While the results indicate promise, suggesting that this combination can help prevent heart damage, further research is needed, especially with higher doses of doxorubicin. Overall, the treatment was well-tolerated by participants.
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
Read More
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
Read More
9
Heart disease control
5 people found this helpful
Once derided, vitamin E now receives significant attention for its role in preventing heart disease. Its natural forms are more effective, and it shows promise for joint inflammation when taken with vitamin A.
Read More
9
Fatigue reduction
4 people found this helpful
After taking this vitamin for a month, I've noticed a reduction in fatigue and improvement in heart support. It's an excellent antioxidant that detoxifies and supports muscle cell restoration.
Read More
9
Heart risk avoidance
2 people found this helpful
I started taking this for heart disease prevention after researching the Shute brothers. I prefer d-alpha tocopherol and feel it supports my heart health effectively.
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Vitamin E is a fat-soluble nutrient that plays a crucial role in various bodily functions, primarily acting as an antioxidant. This means it helps to neutralize free radicals, which are unstable molecules that can cause oxidative stress, leading to cellular damage. Vitamin E is not just one compound, but a group of several related compounds, with tocopherols and tocotrienols being the most studied forms. These compounds are found in various foods, including nuts, seeds, and green leafy vegetables, making it relatively easy to obtain sufficient amounts through a balanced diet.
Research suggests that Vitamin E may contribute to immune function, skin health, and the overall maintenance of cardiovascular health. While most people can get enough Vitamin E from their diet, supplements may be necessary for those with specific deficiencies or conditions that impair absorption. However, it’s important to consult a healthcare provider before starting any supplement regimen, as excessive intake of Vitamin E can lead to adverse effects. Overall, maintaining adequate Vitamin E levels is essential for promoting long-term health and preventing potential deficiencies.
Based on user reviews, it typically takes about four weeks to start seeing results from Vitamin E for heart disease. One user noted that after taking Vitamin E for a month, they noticed a reduction in fatigue and improvement in heart support, emphasizing its effectiveness as an antioxidant Read Review. Additionally, many users report feeling benefits in heart health, energy levels, and overall wellness within similar time frames.
Furthermore, users also highlight that consistent usage is key to achieving and maintaining these benefits. For instance, another user mentioned that they experienced significant contributions to their heart health from taking Vitamin E regularly with meals Read Review. Therefore, it seems prudent to give it a month or so while also adhering to recommended dosages and considering personal health needs.
Recent research suggests that vitamin E may have a beneficial impact on heart health. Studies conducted on large populations, such as one with over 39,000 participants, indicate that higher dietary intake of vitamin E correlates with a significantly lower risk of developing cardiovascular disease and reduced all-cause mortality rates [1]. Similarly, another study found that vitamin E, alongside vitamin B6, is linked to a decreased risk of coronary heart disease (CHD), particularly among certain demographics [2]. These findings position vitamin E as a promising candidate for inclusion in dietary guidelines aimed at heart health.
Furthermore, experimental research has explored the use of vitamin E in various contexts, such as enhancing heart recovery post-acute coronary syndrome and potentially improving heart tissue repair after a heart attack [3], [4]. However, while these findings are encouraging, especially regarding its protective roles in specific situations and patient groups, some studies did not report significant direct benefits of vitamin E in all populations, such as diabetic patients [6]. Overall, while the current body of evidence points to potential benefits of vitamin E for heart health, it is important to approach these findings with a balanced understanding of context and ongoing research needs.
Based on user reviews, many individuals have reported noticeable improvements in various health aspects after incorporating Vitamin E into their routines. A significant number of users highlight enhancements in heart health, specifically noting benefits such as improved circulation and heart function. One user mentioned feeling a reduction in fatigue and overall heart support after just a month of use Read Review. Others have claimed that Vitamin E helps maintain healthy cholesterol levels and supports muscle cell restoration, contributing to their overall well-being and heart health Read Review.
Additionally, some users pointed out benefits extending beyond heart health, including improvements in skin smoothness and reductions in menstrual pain Read Review. While the positive experiences shared are compelling, it's essential to remember that individual results can vary, and the effectiveness of Vitamin E may depend on personal health circumstances and dosage Read Review. Therefore, it is advisable to consult with a healthcare provider before starting any new supplement regimen to ensure that it aligns with individual health needs.
Based on user reviews, many individuals report positive experiences when combining Vitamin E with other supplements to manage heart disease. For example, users emphasize the effectiveness of taking Vitamin E alongside omega acids to enhance absorption and maximize heart health benefits Read Review. Additionally, some users have noted improvements in their gum health when combining Vitamin E with vitamin A, illustrating the potential benefits of such combinations for overall cardiovascular wellness Read Review.
Moreover, many reviews highlight the critical role of Vitamin E as a powerful antioxidant that contributes to heart health when used regularly, yet they also caution against excessive intake due to the risk of blood thinning Read Review. Overall, while numerous users have found great success in using Vitamin E in conjunction with other vitamins, the consensus suggests maintaining prudent dosages and considering personalized health needs, ideally under a healthcare provider's guidance.
Users report varying doses of Vitamin E for treating heart disease, with several indicating that a daily intake of 400 IU is beneficial. For instance, one user emphasized the importance of taking 400 IU daily to protect against heart disease and improve blood circulation Read Review. Another reported noticing significant improvements in heart rhythm and overall heart health after including Vitamin E in their regimen, suggesting that taking it could enhance cardiovascular function Read Review.
That being said, some users advocated for careful dosing, noting that excessive intake may lead to blood thinning effects Read Review. While many reviews highlight the positive impact of Vitamin E on heart health and recommend sticking to the advised dosages, consulting with a physician for personalized guidance is often advised to avoid unwanted side effects and to optimize the benefits of supplementation.
9
Fatigue reduction
4 people found this helpful
After taking this vitamin for a month, I've noticed a reduction in fatigue and improvement in heart support. It's an excellent antioxidant that detoxifies and supports muscle cell restoration.
7.5
Heart health improvement
4 people found this helpful
I take Vitamin E with every meal. It has significantly contributed to my heart health, and I've noticed improvements in my heart rhythm since including it in my routine.
9
Heart health improvement
1 people found this helpful
I've used NOW Natural E-400 w/mixed tocopherols for years. It helps keep my cholesterol under control, and I initially started taking it for heart protection. My doctor says my cholesterol and heart health are good, so it must be effective.
7.5
Heart muscle health
An excellent vitamin that supports heart muscle health. I've found it beneficial overall for my well-being.
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
9
Improves gum condition
When taken with vitamin A, I found that my gums improved in chronic periodontal disease.
6
Blood clotting awareness
1 people found this helpful
All tocopherols act as antioxidants and may help reduce inflammation, potentially aiding heart disease prevention and supporting immune health. However, excessive intake can lead to blood thinning. I take breaks to mitigate these effects.
9
Heart disease protection
22 people found this helpful
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
8
Vitamin E linked to heart health
Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data.
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.
The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.
Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
7
Vitamins E and B6 reduce CHD risk
Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease.
In exploring the connection between vitamins and coronary heart disease (CHD), we analyzed data from a substantial study involving over 33,000 participants from the National Health and Nutrition Examination Survey, covering years 2003-2020.
Our findings revealed that Vitamins E and B6 are associated with a lower risk of CHD, especially among women, individuals with a BMI of 25-30, and smokers. Interestingly, Vitamin B12 showed little impact on heart health.
Overall, our study suggests that increasing Vitamin E and B6 intake might offer protective benefits against heart disease, emphasizing their potential importance in dietary guidelines.
7
Eggs improve heart recovery markers
Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome.
We investigated whether consuming specially enriched hen eggs could improve heart health in patients recovering from acute coronary syndrome. In our randomized clinical trial, one group enjoyed three nutrient-rich eggs daily for three weeks, providing beneficial components like vitamin E.
Our findings showed that these eggs significantly boosted microvascular function without increasing oxidative stress. While there are positive results for microvascular improvements, it is essential to highlight that there was no noted adverse effect, encouraging a closer look at dietary options for heart recovery.
9
Vitamin E hydrogel aids heart repair
Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair.
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.
In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.
While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
7
Vitamin E lacks significant heart benefits
Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease.
We investigated how vitamin E levels relate to heart disease risk in diabetic patients. In this study of 82 individuals with Type 2 diabetes, we found that those also experiencing coronary artery disease had lower levels of vitamin E and other antioxidants.
Notably, higher indicators of oxidative stress were linked to a greater susceptibility to heart disease. However, we observed no significant direct benefits of vitamin E in reducing this risk. Our findings suggest focusing on managing oxidative stress could be vital for preventing heart issues in diabetic patients.
References
Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. doi:10.1016/j.ijcrp.2024.200340
Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. doi:10.1038/s41598-024-68413-8
Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. doi:10.2147/CIA.S461821
Zhang F, Zhang Y, Qian S, Qian X, Jiao J, et al. Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair. ACS Nano. 2024;18:10216. doi:10.1021/acsnano.4c00509
Rivas-Garcia L, Quintana-Navarro GM, Torres-Peña JD, Arenas-de Larriva AP, Alcala-Díaz JF, et al. Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study. Free Radic Biol Med. 2024;210:221. doi:10.1016/j.freeradbiomed.2023.11.026
Mehvari F, Imanparast F, Mohaghegh P, Alimoradian A, Khansari N, et al. Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease. Eur J Med Res. 2023;28:300. doi:10.1186/s40001-023-01254-9
Moustafa I, Connolly C, Anis M, Mustafa H, Oosthuizen F, et al. A prospective study to evaluate the efficacy and safety of vitamin E and levocarnitine prophylaxis against doxorubicin-induced cardiotoxicity in adult breast cancer patients. J Oncol Pharm Pract. 2024;30:354. doi:10.1177/10781552231171114
Reno-Bernstein CM, Oxspring M, Bayles J, Huang EY, Holiday I, et al. Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia. Am J Physiol Endocrinol Metab. 2022;323:E428. doi:10.1152/ajpendo.00188.2022
Heydarnia E, Taghian F, Jalali Dehkordi K, Moghadasi M. Regular combined training and vitamins modulated the apoptosis process in diabetic rats: Bioinformatics analysis of heart failure's differential genes expression network correlated with anti-apoptotic process. J Food Biochem. 2022;46:e14291. doi:10.1111/jfbc.14291
Ojo OO, Obaidu IM, Obigade OC, Olorunsogo OO. Quercetin and vitamin E ameliorate cardio-apoptotic risks in diabetic rats. Mol Cell Biochem. 2022;477:793. doi:10.1007/s11010-021-04332-w
Abdelghffar EA, Obaid WA, Elgamal AM, Daoud R, Sobeh M, et al. Pea (Pisum sativum) peel extract attenuates DOX-induced oxidative myocardial injury. Biomed Pharmacother. 2021;143:112120. doi:10.1016/j.biopha.2021.112120
Asiedu-Gyekye IJ, Arhin E, Arthur SA, N'guessan BB, Amponsah SK. Genotoxicity, nitric oxide level modulation and cardio-protective potential of Kalanchoe Integra Var. Crenata (Andr.) Cuf Leaves in murine models. J Ethnopharmacol. 2022;283:114640. doi:10.1016/j.jep.2021.114640