Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
USERS' SCORE
Good
Based on 24 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%

Top Medical Research Studies

8
Vitamin E linked to heart health
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.

The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.

Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
Read More
9
Vitamin E hydrogel aids heart repair
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.

In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.

While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
Read More
We investigated how vitamin E treatment could impact heart health during severe hypoglycemia in insulin-deficient diabetic rats. In our study, we randomly divided the rats into two groups—those receiving vitamin E and control rats.

Remarkably, we found that treated rats experienced threefold less cardiac oxidative stress, sixfold lower mortality, and sevenfold fewer heart block incidents compared to the controls.

These findings suggest that vitamin E might help reduce fatal heart risks linked to severe hypoglycemia in diabetes, highlighting its potential role in protecting heart health for those suffering from type 1 diabetes.
Read More

Most Useful Reviews

9
Heart disease protection
22 people found this helpful
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
Read More
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
Read More
9
Heart disease control
5 people found this helpful
Once derided, vitamin E now receives significant attention for its role in preventing heart disease. Its natural forms are more effective, and it shows promise for joint inflammation when taken with vitamin A.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.7
  • All Researches
9
Vitamin E hydrogel aids heart repair
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.

In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.

While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
Read More
We investigated how vitamin E treatment could impact heart health during severe hypoglycemia in insulin-deficient diabetic rats. In our study, we randomly divided the rats into two groups—those receiving vitamin E and control rats.

Remarkably, we found that treated rats experienced threefold less cardiac oxidative stress, sixfold lower mortality, and sevenfold fewer heart block incidents compared to the controls.

These findings suggest that vitamin E might help reduce fatal heart risks linked to severe hypoglycemia in diabetes, highlighting its potential role in protecting heart health for those suffering from type 1 diabetes.
Read More
8
Vitamin E linked to heart health
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.

The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.

Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
Read More
We set out to understand how dietary antioxidants influence the thickness of carotid arteries in patients with coronary heart disease (CHD). In a five-year study involving 805 participants, we compared the effects of a Mediterranean diet and a low-fat diet on carotid intima-media thickness (IMT-CC).

Our findings revealed that higher total antioxidant intake was linked to a decrease in IMT-CC, particularly with the Mediterranean diet. This suggests that consuming more antioxidants might help in reducing atherosclerosis progression in these patients.
Read More
8
Vitamin E shows cardioprotective promise
We explored the protective effects of vitamin E and levocarnitine on heart health in women undergoing treatment with doxorubicin for breast cancer. In a well-structured study involving 74 patients, those receiving the vitamin combination experienced significantly lower cardiac enzyme levels and fewer heart-related issues compared to those who did not.

While the results indicate promise, suggesting that this combination can help prevent heart damage, further research is needed, especially with higher doses of doxorubicin. Overall, the treatment was well-tolerated by participants.
Read More

User Reviews

USERS' SCORE
Good
Based on 24 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Heart disease protection
22 people found this helpful
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
Read More
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
Read More
9
Heart disease control
5 people found this helpful
Once derided, vitamin E now receives significant attention for its role in preventing heart disease. Its natural forms are more effective, and it shows promise for joint inflammation when taken with vitamin A.
Read More
9
Fatigue reduction
4 people found this helpful
After taking this vitamin for a month, I've noticed a reduction in fatigue and improvement in heart support. It's an excellent antioxidant that detoxifies and supports muscle cell restoration.
Read More
9
Heart risk avoidance
2 people found this helpful
I started taking this for heart disease prevention after researching the Shute brothers. I prefer d-alpha tocopherol and feel it supports my heart health effectively.
Read More

Frequently Asked Questions

9
Fatigue reduction
4 people found this helpful
After taking this vitamin for a month, I've noticed a reduction in fatigue and improvement in heart support. It's an excellent antioxidant that detoxifies and supports muscle cell restoration.
7.5
Heart health improvement
4 people found this helpful
I take Vitamin E with every meal. It has significantly contributed to my heart health, and I've noticed improvements in my heart rhythm since including it in my routine.
9
Heart health improvement
1 people found this helpful
I've used NOW Natural E-400 w/mixed tocopherols for years. It helps keep my cholesterol under control, and I initially started taking it for heart protection. My doctor says my cholesterol and heart health are good, so it must be effective.
7.5
Heart muscle health
An excellent vitamin that supports heart muscle health. I've found it beneficial overall for my well-being.
9
Heart disease support
22 people found this helpful
Vitamin E is invaluable for heart disease prevention. It's a powerful antioxidant that purifies blood and improves circulation. I find it essential for skin health and use it with omega acids to maximise absorption.
9
Improves gum condition
When taken with vitamin A, I found that my gums improved in chronic periodontal disease.
6
Blood clotting awareness
1 people found this helpful
All tocopherols act as antioxidants and may help reduce inflammation, potentially aiding heart disease prevention and supporting immune health. However, excessive intake can lead to blood thinning. I take breaks to mitigate these effects.
9
Heart disease protection
22 people found this helpful
Wonderful! The strongest antioxidant, Vitamin E—400 IU daily—protects against heart disease. It improves blood circulation, supports protein synthesis, and is essential for reproductive health. I notice my skin becomes smoother while taking it and recommend following your doctor’s advice.
8
Vitamin E linked to heart health
We examined data from over 39,000 people in the NHANES study to see how dietary vitamin E affects heart disease and mortality rates.

The results showed that those consuming more vitamin E had a significantly lower risk of developing cardiovascular disease and lower all-cause mortality rates.

Specifically, participants with higher vitamin E intake experienced a notable decrease in cardiovascular issues, which suggests that a diet rich in vitamin E could be beneficial for heart health and longevity.
7
Vitamins E and B6 reduce CHD risk
In exploring the connection between vitamins and coronary heart disease (CHD), we analyzed data from a substantial study involving over 33,000 participants from the National Health and Nutrition Examination Survey, covering years 2003-2020.

Our findings revealed that Vitamins E and B6 are associated with a lower risk of CHD, especially among women, individuals with a BMI of 25-30, and smokers. Interestingly, Vitamin B12 showed little impact on heart health.

Overall, our study suggests that increasing Vitamin E and B6 intake might offer protective benefits against heart disease, emphasizing their potential importance in dietary guidelines.
7
Eggs improve heart recovery markers
We investigated whether consuming specially enriched hen eggs could improve heart health in patients recovering from acute coronary syndrome. In our randomized clinical trial, one group enjoyed three nutrient-rich eggs daily for three weeks, providing beneficial components like vitamin E.

Our findings showed that these eggs significantly boosted microvascular function without increasing oxidative stress. While there are positive results for microvascular improvements, it is essential to highlight that there was no noted adverse effect, encouraging a closer look at dietary options for heart recovery.
9
Vitamin E hydrogel aids heart repair
We explored the use of an innovative hydrogel loaded with α-tocopherol (vitamin E) to promote heart tissue repair after a heart attack.

In experiments conducted on rabbits, the injectable hydrogel showed impressive results within four weeks, significantly improving heart function and reducing damaged areas.

While this study highlights the potential of vitamin E in enhancing recovery, it's essential to note that further research is needed to fully understand its effectiveness in human patients.
7
Vitamin E lacks significant heart benefits
We investigated how vitamin E levels relate to heart disease risk in diabetic patients. In this study of 82 individuals with Type 2 diabetes, we found that those also experiencing coronary artery disease had lower levels of vitamin E and other antioxidants.

Notably, higher indicators of oxidative stress were linked to a greater susceptibility to heart disease. However, we observed no significant direct benefits of vitamin E in reducing this risk. Our findings suggest focusing on managing oxidative stress could be vital for preventing heart issues in diabetic patients.

References

  1. Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. doi:10.1016/j.ijcrp.2024.200340
  2. Li B, Hu M, Ma Y, Sun X, Wu D, et al. Association between Vitamin E, Vitamin B6, and Vitamin B12 with coronary heart disease. Sci Rep. 2024;14:19960. doi:10.1038/s41598-024-68413-8
  3. Masle AM, Kibel A, Jukić I, Čičak P, Selthofer-Relatić K, et al. Enhancing Endothelial Function with Nutrient-Enriched Table Hen Eggs: A Randomized Study in Patients Recovering from Acute Coronary Syndrome. Clin Interv Aging. 2024;19:953. doi:10.2147/CIA.S461821
  4. Zhang F, Zhang Y, Qian S, Qian X, Jiao J, et al. Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair. ACS Nano. 2024;18:10216. doi:10.1021/acsnano.4c00509
  5. Rivas-Garcia L, Quintana-Navarro GM, Torres-Peña JD, Arenas-de Larriva AP, Alcala-Díaz JF, et al. Dietary antioxidant intake reduces carotid intima-media thickness in coronary heart disease patients: From the CORDIOPREV study. Free Radic Biol Med. 2024;210:221. doi:10.1016/j.freeradbiomed.2023.11.026
  6. Mehvari F, Imanparast F, Mohaghegh P, Alimoradian A, Khansari N, et al. Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease. Eur J Med Res. 2023;28:300. doi:10.1186/s40001-023-01254-9
  7. Moustafa I, Connolly C, Anis M, Mustafa H, Oosthuizen F, et al. A prospective study to evaluate the efficacy and safety of vitamin E and levocarnitine prophylaxis against doxorubicin-induced cardiotoxicity in adult breast cancer patients. J Oncol Pharm Pract. 2024;30:354. doi:10.1177/10781552231171114
  8. Reno-Bernstein CM, Oxspring M, Bayles J, Huang EY, Holiday I, et al. Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia. Am J Physiol Endocrinol Metab. 2022;323:E428. doi:10.1152/ajpendo.00188.2022
  9. Heydarnia E, Taghian F, Jalali Dehkordi K, Moghadasi M. Regular combined training and vitamins modulated the apoptosis process in diabetic rats: Bioinformatics analysis of heart failure's differential genes expression network correlated with anti-apoptotic process. J Food Biochem. 2022;46:e14291. doi:10.1111/jfbc.14291
  10. Ojo OO, Obaidu IM, Obigade OC, Olorunsogo OO. Quercetin and vitamin E ameliorate cardio-apoptotic risks in diabetic rats. Mol Cell Biochem. 2022;477:793. doi:10.1007/s11010-021-04332-w
  11. Abdelghffar EA, Obaid WA, Elgamal AM, Daoud R, Sobeh M, et al. Pea (Pisum sativum) peel extract attenuates DOX-induced oxidative myocardial injury. Biomed Pharmacother. 2021;143:112120. doi:10.1016/j.biopha.2021.112120
  12. Asiedu-Gyekye IJ, Arhin E, Arthur SA, N'guessan BB, Amponsah SK. Genotoxicity, nitric oxide level modulation and cardio-protective potential of Kalanchoe Integra Var. Crenata (Andr.) Cuf Leaves in murine models. J Ethnopharmacol. 2022;283:114640. doi:10.1016/j.jep.2021.114640
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